Background: Although simulation is a well-established learning method in Finland, sequential simulations are still uncommon. The objective of this project was to pilot interprofessional, sequential simulation demonstrating acute clinical pathways. The learning objectives were communication and collaboration. Methods: Two groups consisting of nursing and emergency care students planned the simulation exercises. Other participants in the simulation were medical students, biomedical science students and radiography students. Results: Participants considered the sequential simulation were a good learning method particularly for skills in communication, patient encounters and working in an interprofessional setting. Conclusions: An interprofessional, sequential simulation of a clinical pathway is a good method to practice non-technical skills. Sequential simulation also helps students understand the whole health care system.